(R, S, S) -VH032
(R, R, S) -VH032 is a VHL E3 ligase ligand used to construct PROTAC degraders, such as the tau-targeting molecule C004019. It disrupts the VHL/HIF-1α interaction and has been employed in both cellular and in vivo studies to develop targeted protein degradation therapies for neurodegenerative and oncological research.
Product Specifications
CAS Number
2230826-33-0
Field of Research
Pharmacology & Drug Discovery
Smiles
C (NCC1=CC=C (C=C1) C=2SC=NC2C) (=O) [C@@H]3N (C ([C@H] (C (C) (C) C) N) =O) C[C@@H] (O) C3
Molecular Formula
C22H30N4O3S
Molecular Weight
430.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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