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Lenalidomide 4'-alkyl-C3-azide

Lenalidomide 4'-alkyl-C3-azide (4a) is a cereblon (CRBN) ligand derivatized with an azide handle for bioorthogonal conjugation via CuAAC or SPAAC chemistry. It is a key building block for constructing PROTAC degraders, enabling targeted protein degradation research in both cellular and preclinical models.

Product Specifications

CAS Number

2399455-71-9

Field of Research

Pharmacology & Drug Discovery

Smiles

N (CCCN=[N+]=[N-]) C1=C2C (C (=O) N (C2) C3C (=O) NC (=O) CC3) =CC=C1

Molecular Formula

C16H18N6O3

Molecular Weight

342.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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