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PROTAC (H-PGDS) -8

PROTAC (H-PGDS) -8 is a potent small molecule degrader of Hematopoietic Prostaglandin D Synthase (H-PGDS), demonstrating an IC50 of 0.14 μM. This compound is a valuable research tool for investigating H-PGDS function in inflammatory and allergic disease models, both in vitro and in vivo.

Product Specifications

CAS Number

2761281-51-8

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Smiles

O=C1C2=C (C=CC=C2C (=O) N1C3C (=O) N (C) C (=O) CC3) N4CCN (C (=O) C5CCN (CC5) C6=CC=C (NC (=O) C=7C=NC (OC8=CC=CC=C8) =NC7) C=C6) CC4

Molecular Formula

C41H40N8O7

Molecular Weight

756.81

Storage Conditions

-20°C

Notes

For research use only.

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