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VH 101, thiol

VH 101 (compound 20) is a thiol-based VHL ligand used for constructing PROTAC degraders. This key chemical tool enables targeted protein degradation research in both cellular and in vivo models for probing disease biology and therapeutic pathways.

Product Specifications

CAS Number

2358775-81-0

Field of Research

Pharmacology & Drug Discovery

Smiles

C ([C@@H] (NC (=O) C1 (F) CC1) [C@@] (C) (C) S) (=O) N2[C@H] (C (NCC3=CC=C (C=C3) C4=C (C) N=CS4) =O) C[C@@H] (O) C2

Molecular Formula

C25H31FN4O4S2

Molecular Weight

534.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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