PF-4348235 HCl
PF-4348235 HCl is a dual-action MABA compound, functioning as a potent M3 muscarinic receptor antagonist (Ki: 0.73 nM) and a β2-adrenoceptor agonist (EC50: 3.7 nM) . It serves as a research bronchodilator for investigating therapeutic strategies in respiratory diseases like COPD, utilizing both in vitro binding assays and in vivo preclinical models.
Product Specifications
Product Name Alternative
M3 mAChR, AdrenergicReceptor, Adrenergic Receptor, PF-4348235 HCl (1017857-38-3 Free base), β2AR/M-receptor agonist-2 HCl, β2AR/Mreceptoragonist2HCl (1017857383Freebase), β2-adrenergic receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.81% (May vary between batches)
Smiles
O[C@H] (C1=CC (NS (C) (=O) =O) =C (C=C1) O) CNCCCCCCCCCN (CC2) CCC2OC (NC3=C (C4=CC (Cl) =C (C=C4) O) C=CC=C3) =O.Cl
Molecular Formula
C36H50Cl2N4O7S
Molecular Weight
753.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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