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WJ-39

WJ-39 is an orally bioavailable aldose reductase inhibitor that activates Nrf2 signaling and suppresses NLRP3 inflammasome-driven oxidative stress and inflammation. It has demonstrated efficacy in ameliorating diabetic nephropathy, renal insufficiency, and fibrosis in preclinical in vivo studies.

Product Specifications

CAS Number

3009908-95-3

Product Name Alternative

Aldose reductase, WJ 39, WJ39

Field of Research

Cell Biology, Metabolism Research

Purity

99.45% (May vary between batches)

Solubility

DMSO:100 mg/mL (232.39 mM)

Smiles

O=C (CN1C=C (CC2=C (Cl) C (Cl) =CC=C2) C (C3=CC (OC) =CC=C31) =O) [O-].[K+]

Molecular Formula

C19H14Cl2KNO4

Molecular Weight

430.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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