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Halofuginone hydrochloride

Halofuginone hydrochloride is a potent, 18.3 nM Ki competitive inhibitor of prolyl-tRNA synthetase. It is widely used in research for its anti-fibrotic, anti-inflammatory, and anti-cancer properties, with applications in studying TGF-β signaling, collagen synthesis, and pulmonary hypertension in both in vitro and in vivo models.

Product Specifications

CAS Number

1217623-74-9

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Smiles

Cl.OC1CCCN[C@H]1CC (=O) Cn1cnc2cc (Br) c (Cl) cc2c1=O

Molecular Formula

C16H18BrCl2N3O3

Molecular Weight

451.14

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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