1-Aminodecylidene bis-Phosphonic Acid
1-Aminodecylidenebis-phosphonic acid is a potent and selective acid sphingomyelinase inhibitor (IC50= 20 nM), showing >5000-fold selectivity over neutral sphingomyelinase. It effectively blocks dexamethasone-induced apoptosis in HepG2 cells in vitro, making it a valuable research tool for studying ceramide-mediated pathways in apoptosis and liver disease models.
Product Specifications
CAS Number
15049-93-1
Field of Research
Metabolism Research
Smiles
C (CCCCCCCCC) (P (=O) (O) O) (P (=O) (O) O) N
Molecular Formula
C10H25NO6P2
Molecular Weight
317.26
Storage Conditions
-20°C
Notes
For research use only.
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