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F-Amidine TFA

F-amidine is a selective, irreversible inhibitor of protein arginine deiminases (PADs), particularly PAD1 and PAD4. It covalently modifies an active site cysteine, inactivating the enzymes. This compound also exhibits cytotoxic activity against several cancer cell lines, supporting its use in researching PAD-related pathways in cancer and autoimmune diseases.

Product Specifications

CAS Number

877617-46-4

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation

Smiles

C (C (O) =O) (F) (F) F.C (N[C@@H] (CCCNC (CF) =N) C (N) =O) (=O) C1=CC=CC=C1

Molecular Formula

C14H19FN4O2?CF3COOH

Molecular Weight

408.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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