F-Amidine TFA
F-amidine is a selective, irreversible inhibitor of protein arginine deiminases (PADs), particularly PAD1 and PAD4. It covalently modifies an active site cysteine, inactivating the enzymes. This compound also exhibits cytotoxic activity against several cancer cell lines, supporting its use in researching PAD-related pathways in cancer and autoimmune diseases.
Product Specifications
CAS Number
877617-46-4
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation
Smiles
C (C (O) =O) (F) (F) F.C (N[C@@H] (CCCNC (CF) =N) C (N) =O) (=O) C1=CC=CC=C1
Molecular Formula
C14H19FN4O2?CF3COOH
Molecular Weight
408.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2913423-01 20 µg
Recombinant Pseudomonas fluorescens Macrolide export ATP-binding/permease protein MacB 1 (macB1)
Sign In for Pricing
View Details orb2913423-02 100 µg
Recombinant Pseudomonas fluorescens Macrolide export ATP-binding/permease protein MacB 1 (macB1)
Sign In for Pricing
View Details