CAY10649
1CAY10649 is a potent thiazolinone inhibitor of 5-lipoxygenase (5-LO), effectively blocking leukotriene biosynthesis in both intact PMNLs (IC50=0.28 μM) and cell lysates (IC50=0.09 μM) . This mechanism supports its research utility in studying inflammatory pathways, including neutrophil chemotaxis and vascular permeability, in cellular and biochemical assays.
Product Specifications
CAS Number
1272519-89-7
Field of Research
Neuroscience
Smiles
C (=C/1\SC (=NC1=O) C2=CC=C (Cl) C=C2) \C3=CC=C (OC) C=C3
Molecular Formula
C17H12ClNO2S
Molecular Weight
329.8
Storage Conditions
-20°C
Notes
For research use only.
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