SB 203580 sulfone
SB 203580 sulfone is a p38 MAPK inhibitor analog that competitively binds CSBP proteins, blocking stress signaling. It inhibits IL-1 production in monocytes with an IC50 of 0.2 μM and CSBP-mediated signaling with an IC50 of 0.03 μM. This compound is a valuable tool for studying inflammatory pathways in cellular models.
Product Specifications
CAS Number
152121-46-5
Field of Research
Signal Transduction
Smiles
FC1=CC=C (C2=C (N=C (N2) C3=CC=C (S (C) (=O) =O) C=C3) C=4C=CN=CC4) C=C1
Molecular Formula
C21H16FN3O2S
Molecular Weight
393.43
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
