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SB 203580 sulfone

SB 203580 sulfone is a p38 MAPK inhibitor analog that competitively binds CSBP proteins, blocking stress signaling. It inhibits IL-1 production in monocytes with an IC50 of 0.2 μM and CSBP-mediated signaling with an IC50 of 0.03 μM. This compound is a valuable tool for studying inflammatory pathways in cellular models.

Product Specifications

CAS Number

152121-46-5

Field of Research

Signal Transduction

Smiles

FC1=CC=C (C2=C (N=C (N2) C3=CC=C (S (C) (=O) =O) C=C3) C=4C=CN=CC4) C=C1

Molecular Formula

C21H16FN3O2S

Molecular Weight

393.43

Storage Conditions

-20°C

Notes

For research use only.

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