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(Z) -RG-13022

(Z) -RG-13022 is a selective EGFR tyrosine kinase inhibitor with an IC50 of 11 μM for DNA synthesis in HN5 cells, demonstrating threefold greater potency than its (E) -isomer. This compound is used in breast cancer research to study EGFR-driven cell proliferation in vitro.

Product Specifications

CAS Number

149286-90-8

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

C (=C (\C#N) /C=1C=CC=NC1) \C2=CC (OC) =C (OC) C=C2

Molecular Formula

C16H14N2O2

Molecular Weight

266.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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