(Z) -RG-13022
(Z) -RG-13022 is a selective EGFR tyrosine kinase inhibitor with an IC50 of 11 μM for DNA synthesis in HN5 cells, demonstrating threefold greater potency than its (E) -isomer. This compound is used in breast cancer research to study EGFR-driven cell proliferation in vitro.
Product Specifications
CAS Number
149286-90-8
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
C (=C (\C#N) /C=1C=CC=NC1) \C2=CC (OC) =C (OC) C=C2
Molecular Formula
C16H14N2O2
Molecular Weight
266.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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