5 (S) -HEPE
5 (S) -HEPE, a 5-lipoxygenase-derived metabolite of EPA, acts as a GPR119 agonist to stimulate cAMP production. It enhances glucose-dependent insulin secretion in MING6 cells and GLP-1 release in HuTu 80 cells at 10 μM, with research applications in metabolic studies, including investigations into hyperlipidemia where its serum levels are elevated.
Product Specifications
CAS Number
92008-51-0
Smiles
[C@@H] (/C=C/C=C\C/C=C\C/C=C\C/C=C\CC) (CCCC (O) =O) O
Molecular Formula
C20H30O3
Molecular Weight
318.5
Storage Conditions
-20°C
Notes
For research use only.
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