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5 (S) -HEPE

5 (S) -HEPE, a 5-lipoxygenase-derived metabolite of EPA, acts as a GPR119 agonist to stimulate cAMP production. It enhances glucose-dependent insulin secretion in MING6 cells and GLP-1 release in HuTu 80 cells at 10 μM, with research applications in metabolic studies, including investigations into hyperlipidemia where its serum levels are elevated.

Product Specifications

CAS Number

92008-51-0

Smiles

[C@@H] (/C=C/C=C\C/C=C\C/C=C\C/C=C\CC) (CCCC (O) =O) O

Molecular Formula

C20H30O3

Molecular Weight

318.5

Storage Conditions

-20°C

Notes

For research use only.

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