244cis
The cationic lipid 244cis, featuring a piperazine group, enables the formulation of mRNA-loaded lipid nanoparticles (LNPs) with enhanced lung tropism in mice compared to SM-102-based LNPs, while also reducing serum CCL2 levels. This makes it a valuable tool for research in pulmonary-targeted gene delivery and immunology.
Product Specifications
CAS Number
2956402-64-3
Field of Research
Metabolism Research
Smiles
C (CN (CCCCCCCCC (OC/C=C\CCCCCC) =O) CCCCCCCCC (OC/C=C\CCCCCC) =O) N1CCN (CCCCCCCCC (OC/C=C\CCCCCC) =O) CC1
Molecular Formula
C60H111N3O6
Molecular Weight
970.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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