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NPBA

NPBA is a dual-function small molecule that acts as a TASK-3 (KCNK9) channel agonist and a TWIK2 channel blocker. This activity enables it to potently suppress NLRP3 inflammasome activation in macrophages, making it a valuable research tool for studying inflammation and potassium channel biology in both cellular and animal models.

Product Specifications

CAS Number

524033-40-7

Field of Research

Pharmacology & Drug Discovery

Purity

99.90% (May vary between batches)

Smiles

O=C (C1=CC=CC=C1) NCCNC2=CC=C ([N+] ([O-]) =O) C=C2C (F) (F) F

Molecular Formula

C16H14F3N3O3

Molecular Weight

353.30

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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