NPBA
NPBA is a dual-function small molecule that acts as a TASK-3 (KCNK9) channel agonist and a TWIK2 channel blocker. This activity enables it to potently suppress NLRP3 inflammasome activation in macrophages, making it a valuable research tool for studying inflammation and potassium channel biology in both cellular and animal models.
Product Specifications
CAS Number
524033-40-7
Field of Research
Pharmacology & Drug Discovery
Purity
99.90% (May vary between batches)
Smiles
O=C (C1=CC=CC=C1) NCCNC2=CC=C ([N+] ([O-]) =O) C=C2C (F) (F) F
Molecular Formula
C16H14F3N3O3
Molecular Weight
353.30
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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