(S) -Sabutoclax
(S) -Sabutoclax is an optically active pan-inhibitor of antiapoptotic Bcl-2 family proteins, effectively displacing BH3 peptides from Bcl-XL, Bcl-2, Mcl-1, and Bfl-1. It demonstrates potent, sub-micromolar growth inhibition in various cancer cell lines and is a key research tool for studying apoptosis in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
1228178-73-1
Field of Research
Cell Biology
Smiles
CC1=CC2=C (C (NC[C@@H] (C3=CC=CC=C3) C) =O) C (O) =C (O) C=C2C (O) =[C@]1[C@]4=C (C) C=C5C (C (NC[C@@H] (C6=CC=CC=C6) C) =O) =C (O) C (O) =CC5=C4O
Molecular Formula
C42H42N2O8S
Molecular Weight
732.84
Storage Conditions
-20°C
Notes
For research use only.
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