Dasatinib analog-1
Dasatinib analog-1 (compound 5826) is a research compound that inhibits CYP3A4 enzyme activity with a K_i of 5.4 μM and reduces glutathione adduct formation. It serves as a useful pharmacological tool for in vitro studies investigating drug metabolism, toxicity mechanisms, and cytochrome P450 interactions.
Product Specifications
CAS Number
1174416-41-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
N (C1=CC (N2CCN (CCO) CC2) =NC (C) =N1) C=3SC (C (NC4=C (C) C=C (F) C=C4Cl) =O) =CN3
Molecular Formula
C22H25ClFN7O2S
Molecular Weight
506
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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