MMAF-OtBu
MMAF-OtBu is a tert-butyl ester derivative of the cytotoxic agent MMAF, designed for the synthesis of antibody-drug conjugates (ADCs) . This microtubule-disrupting payload is widely used in ADC research for evaluating antitumor efficacy in both in vitro cytotoxicity assays and in vivo xenograft models.
Product Specifications
CAS Number
745017-95-2
Product Name Alternative
ADCCytotoxin
Field of Research
Signal Transduction
Purity
98.94% (May vary between batches)
Solubility
DMSO:40 mg/mL (50.76 mM)
Smiles
[C@H] ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (OC (C) (C) C) =O) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@H] (C (C) C) NC) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C43H73N5O8
Molecular Weight
788.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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