(1S) -CCR2 antagonist 1
(1S) -CCR2 antagonist 1 is the levorotatory enantiomer of a potent CCR2 antagonist, demonstrating high binding affinity (Ki = 2.4 nM) and an extended receptor residence time. This compound is a valuable research tool for investigating CCR2-mediated pathways in inflammatory and autoimmune diseases, applicable in both in vitro binding assays and in vivo model studies.
Product Specifications
CAS Number
1683534-97-5
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
C (=O) ([C@]1 ([C@@H] (C) C) C[C@H] (N[C@@H]2C=3C (CC2) =CC (Br) =CC3) CC1) N4CC=5C (CC4) =CC=C (C (F) (F) F) C5
Molecular Formula
C28H32BrF3N2O
Molecular Weight
549.47
Storage Conditions
-20°C
Notes
For research use only.
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