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Topoisomerase IIα-IN-8

Topoisomerase IIα-IN-8 (compound 15) is a small molecule inhibitor of human topoisomerase IIα (htIIα) with a moderate IC50 of 462 ± 38.0 μM. This tool compound is suitable for in vitro biochemical studies investigating topoisomerase IIα function and for research in fields such as cancer biology and DNA replication.

Product Specifications

CAS Number

1251578-67-2

Field of Research

Molecular Biology

Smiles

FC1=CC=C (NC2=NC3=C (N=CN3) C (=N2) N2CCOCC2) C=C1

Molecular Formula

C15H15FN6O

Molecular Weight

314.324

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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