(S) -Ro 32-0432
(S) -Ro 32-0432 is a potent, orally active, and ATP-competitive inhibitor of PKC isoforms (IC50: 9.3-108.3 nM) and GRK5. Its inhibition of T-cell activation supports its use in research models for autoimmune and inflammatory diseases, both in vitro and in vivo.
Product Specifications
CAS Number
1781828-85-0
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
O=C1C (C2=C3N (C=4C2=CC=CC4) CC[C@H] (CN (C) C) C3) =C (C (=O) N1) C=5C=6C (N (C) C5) =CC=CC6.Cl
Molecular Formula
C28H29ClN4O2
Molecular Weight
489.01
Storage Conditions
-20°C
Notes
For research use only.
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