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LU-005i

LU-005i is a potent and selective small molecule inhibitor of the immunoproteasome subunit β5i (IC50 = 6.6 nM), showing >40-fold selectivity over the constitutive proteasome subunit β5c. This inhibitor is a valuable research tool for studying immunoproteasome function in autoimmune disease and cancer models, both in vitro and in vivo.

Product Specifications

CAS Number

1620107-33-6

Field of Research

Protein Biochemistry

Smiles

C ([C@H] (CC1CCCCC1) NC ([C@H] (CC2=CC=C (OC) C=C2) NC ([C@@H] (NC (CN3CCOCC3) =O) C) =O) =O) (=O) [C@@]4 (C) CO4

Molecular Formula

C31H46N4O7

Molecular Weight

586.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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