LU-005i
LU-005i is a potent and selective small molecule inhibitor of the immunoproteasome subunit β5i (IC50 = 6.6 nM), showing >40-fold selectivity over the constitutive proteasome subunit β5c. This inhibitor is a valuable research tool for studying immunoproteasome function in autoimmune disease and cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
1620107-33-6
Field of Research
Protein Biochemistry
Smiles
C ([C@H] (CC1CCCCC1) NC ([C@H] (CC2=CC=C (OC) C=C2) NC ([C@@H] (NC (CN3CCOCC3) =O) C) =O) =O) (=O) [C@@]4 (C) CO4
Molecular Formula
C31H46N4O7
Molecular Weight
586.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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