PH-HG-005-5
PH-HG-005-5 (compound 16c) is a SN-38-based drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs) . It enables site-specific coupling to targeting antibodies for cancer research, facilitating the evaluation of ADC efficacy in both in vitro cytotoxicity assays and in vivo xenograft models.
Product Specifications
CAS Number
2810895-93-1
Smiles
O (C (OCC1=CC=C (NC ([C@@H] (NC ([C@H] (C (C) C) N) =O) CCCNC (N) =O) =O) C=C1) =O) [C@@]2 (CC) C3=C (C (=O) N4C (=C3) C=5C (C4) =C (CC) C=6C (N5) =CC=C (O) C6) COC2=O
Molecular Formula
C41H47N7O10
Molecular Weight
797.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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