MDPR-Val-Cit-PAB-MMAE TFA
MDPR-Val-Cit-PAB-MMAE TFA is a cleavable drug-linker conjugate for constructing Antibody-Drug Conjugates (ADCs) . It incorporates the potent antimitotic agent MMAE, which is released upon protease cleavage, enabling targeted cytotoxicity in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
2185872-76-6
Field of Research
Immunology & Inflammation
Smiles
C (C (O) =O) (F) (F) F.[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CN) N4C (=O) C=CC4=O) =O) [C@@H] (C) C) =O) CCCNC (N) =O) =O) C=C3) =O) C) C (C) C) =O) [C@@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C67H101F3N12O17
Molecular Weight
1403.58
Storage Conditions
-20°C
Notes
For research use only.
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