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11alpha-Hydroxyprogesterone

11alpha-Hydroxyprogesterone is an inactive control compound, while its stereoisomer 11beta-Hydroxyprogesterone is a potent 11β-HSD inhibitor and a human mineralocorticoid receptor agonist (ED50 = 10 nM in COS-7 cells) . This small molecule is used in vitro to study steroid metabolism, receptor activation, and hypertension-related pathways.

Product Specifications

CAS Number

80-75-1

Field of Research

Metabolism Research

Smiles

[H][C@@]12CC[C@H] (C (C) =O) [C@@]1 (C) C[C@@H] (O) [C@@]1 ([H]) [C@@]2 ([H]) CCC2=CC (=O) CC[C@]12C

Molecular Formula

C21H30O3

Molecular Weight

330.468

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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