PRT543
PRT543 is a potent and selective PRMT5 inhibitor, demonstrating broad-spectrum antitumor activity in both cellular and animal models. It effectively inhibits the PRMT5/MEP50 methyltransferase complex with an IC50 of 10.8 nM, making it a valuable tool for oncology research, particularly in studying hematological and solid tumor malignancies.
Product Specifications
CAS Number
1989620-03-2
Field of Research
Epigenetics & Chromatin
Smiles
O[C@H]1[C@H] (N2C=3C (C=C2) =C (N) N=CN3) O[C@] ([C@H] (O) C4=CC=C (Cl) C=C4) ([C@H]1O) [H]
Molecular Formula
C17H17ClN4O4
Molecular Weight
376.79
Storage Conditions
-20°C
Notes
For research use only.
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