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Hexacyclen

Hexacyclen is a polyazamacrocycle analog of 18-crown-6 that acts as an extracellular calcium-sensing receptor (CaSR) antagonist with an EC50 of 20 μM. Its multiple secondary amines make it a strong electron donor, useful in polymer chemistry and for studying CaSR function in cellular assays.

Product Specifications

CAS Number

296-35-5

Product Name Alternative

Hexaaza-18-crown-6, 1,4,7,10,13,16-Hexazacyclooctadecane

Solubility

H2O:80 mg/mL (309.59 mM)

Smiles

N1CCNCCNCCNCCNCCNCC1

Molecular Formula

C12H30N6

Molecular Weight

258.41

Storage Conditions

-20°C

Notes

For research use only.

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