Cis-J-113863
Cis-J-113863 is a potent and selective competitive antagonist of the chemokine receptor CCR1, exhibiting IC50 values of 0.9 nM (human) and 5.8 nM (mouse) . It is a valuable research tool for studying CCR1-mediated inflammatory and autoimmune pathways in both cellular assays and animal disease models.
Product Specifications
CAS Number
202796-41-6
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
C (N[C@@H]1CC[N@@+] (CC=2CCCCCCC2) (CC) CC1) (=O) C3C=4C (OC=5C3=CC (Cl) =CC5) =CC=C (Cl) C4.[I-]
Molecular Formula
C30H37Cl2IN2O2
Molecular Weight
655.44
Storage Conditions
-20°C
Notes
For research use only.
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