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Trans-J-113863

Trans-J-113863 is a potent dual antagonist of chemokine receptors CCR1 and CCR3, with IC50 values of 9.57 nM and 93.8 nM against MIP-1α and eotaxin-induced chemotaxis, respectively. It is a valuable research tool for studying allergic inflammation, asthma, and other CCR1/CCR3-mediated pathways in both cellular and animal models.

Product Specifications

CAS Number

202796-42-7

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

C (N[C@@H]1CC[N@+] (CC=2CCCCCCC2) (CC) CC1) (=O) C3C=4C (OC=5C3=CC (Cl) =CC5) =CC=C (Cl) C4.[I-]

Molecular Formula

C30H37Cl2IN2O2

Molecular Weight

655.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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