FHT-2344
FHT-2344 is a potent dual inhibitor of the SWI/SNF ATPases SMARCA4 and SMARCA2, with IC50 values of 26 nM and 13 nM, respectively. It is a valuable chemical probe for investigating SWI/SNF function in oncology research, demonstrating activity in both cellular and in vivo models of SMARCA4-deficient cancers.
Product Specifications
CAS Number
2468058-90-2
Field of Research
Epigenetics & Chromatin
Smiles
N (C ([C@@H] (NC (=O) C1=CN (S (C) (=O) =O) C=C1) COC) =O) C2=NC (C3=CC (=CC=C3) C4=NN (C) C=C4) =CS2
Molecular Formula
C23H24N6O5S2
Molecular Weight
528.6
Storage Conditions
-20°C
Notes
For research use only.
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