Cytarabine 5′-monophosphate
Cytarabine 5′-monophosphate (ara-CMP) is the active phosphorylated metabolite of the antimetabolite cytarabine. It functions by incorporating into DNA via DNA polymerase α, thereby inhibiting DNA replication. This mechanism has demonstrated efficacy in research models, including the inhibition of yeast replication in vitro and improved survival in murine leukemia studies in vivo.
Product Specifications
CAS Number
7075-11-8
Field of Research
Cell Biology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Smiles
Nc1ccn ([C@@H]2O[C@H] (COP (O) (O) =O) [C@@H] (O) [C@@H]2O) c (=O) n1
Molecular Formula
C9H14N3O8P
Molecular Weight
323.198
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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