(±) -N-desmethyl Venlafaxine hydrochloride
(±) -N-desmethyl Venlafaxine is an active SNRI metabolite of venlafaxine, formed via CYP3A4. In vitro, it inhibits norepinephrine and serotonin reuptake (IC50 = 4.7 and 1.6 μM in rat synaptosomes), and in vivo, it reverses reserpine-induced hypothermia in mice (MED = 10 mg/kg) .
Product Specifications
CAS Number
93413-90-2
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
Cl.CNCC (c1ccc (OC) cc1) C1 (O) CCCCC1
Molecular Formula
C16H26ClNO2
Molecular Weight
299.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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