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(±) -N-desmethyl Venlafaxine hydrochloride

(±) -N-desmethyl Venlafaxine is an active SNRI metabolite of venlafaxine, formed via CYP3A4. In vitro, it inhibits norepinephrine and serotonin reuptake (IC50 = 4.7 and 1.6 μM in rat synaptosomes), and in vivo, it reverses reserpine-induced hypothermia in mice (MED = 10 mg/kg) .

Product Specifications

CAS Number

93413-90-2

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

Cl.CNCC (c1ccc (OC) cc1) C1 (O) CCCCC1

Molecular Formula

C16H26ClNO2

Molecular Weight

299.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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