Indium (III) thiosemicarbazone 5b
Indium (III) thiosemicarbazone 5b is a cytotoxic agent effective against multiple cancer cell lines, including cisplatin-resistant MCF-7/DDP cells, by inhibiting PI3K/Akt/mTOR signaling and reducing P-gp. In vivo, it suppresses tumor growth in xenograft models, and liposomal formulations enhance its pro-apoptotic and autophagic activity, supporting its study in oncology and drug resistance research.
Product Specifications
CAS Number
2345755-20-4
Smiles
[OH] (C) [In+3]12 ([Cl-]) ([Cl-]) [N]=3C (C=[N]1N=C (N (C) C) [S-]2) =CC=CC3
Molecular Formula
C10H15Cl2InN4OS
Molecular Weight
425.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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