Phenylephrine (Standard)

Phenylephrine (Standard) is the analytical standard of Phenylephrine. This product is intended for research and analytical applications. (R) - (-) -Phenylephrine is a selective α1-adrenoceptor agonist primarily used as a decongestant.

Product Specifications

CAS Number

[59-42-7]

Product Name Alternative

(R) - (-) -Phenylephrine (Standard) ; L-Phenylephrine (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H318, H335

Target

Adrenergic Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/phenylephrine-standard.html

Purity

99.96

Smiles

O[C@H](C1=CC(O)=CC=C1)CNC

Molecular Formula

C9H13NO2

Molecular Weight

167.21

Precautions

H302, H315, H318, H335

References & Citations

[1]Ford AP, et al. Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications foralpha1-adrenoceptor classification. Br J Pharmacol. 1997 Jul;121 (6) :1127-35.|[2]Minneman KP, et al. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Mol Pharmacol. 1994 Nov;46 (5) :929-36.|[3]Wang J, et al. Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway. Front Biosci (Landmark Ed) . 2016 Jan 1;21:502-13.|[4]Lazou A, et al. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. Biochem J. 1998 Jun 1;332 (Pt 2) :459-65.|[5]Li NJ, et al. Effect of phenylephrine on alveolar fluid clearance in ventilator-induced lung injury. Chin Med Sci J. 2013 Mar;28 (1) :1-6.