Myrothecine A
Myrothecine A is a trichothecene mycotoxin with anticancer activity, inhibiting proliferation in A549, MCF-7, HepG2, and SMMC-7721 cells. It induces G1 phase arrest and promotes apoptosis via increased Bax and cleaved caspases, supporting its use in oncology and cell biology research for studying cytotoxic mechanisms.
Product Specifications
CAS Number
910292-40-9
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction
Smiles
CC (=O) C12CC\C=C/C (=O) OC3CC4OC5C6CC4 (O) C3 (C) C5 (CCC6 (C) O) COC (=O) \C=C (\CCO1) C2O |c:6, t:36, TLB:13:18:25.24.23:15,11:20:25.24.23:15,19:18:25.24.23:15, THB:25:16:22.20:13.14,19:18:22.15.14:12.11,17:18:22.15.14:12.11,21:20:25.24.23:15|
Molecular Formula
C29H38O10
Molecular Weight
546.61
Storage Conditions
-20°C
Notes
For research use only.
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