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7-keto-25-hydroxy Cholesterol

This oxysterol metabolite of 7-keto and 7-dehydro cholesterol is a Smoothened (Smo) agonist, binding to its extracellular cysteine-rich domain. It also modulates EGF receptor affinity in NRK cells, making it a valuable tool for studying Hedgehog signaling and receptor biology in vitro.

Product Specifications

CAS Number

64907-23-9

Field of Research

Metabolism Research, Stem Cell & Developmental Biology

Smiles

C[C@H] (CCCC (C) (C) O) [C@H]1CC[C@H]2[C@H]3[C@H] (CC[C@]12C) [C@@]1 (C) CC[C@H] (O) CC1=CC3=O

Molecular Formula

C27H44O3

Molecular Weight

416.646

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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