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N-Boc-2-pyrroleboronic acid

N-Boc-2-pyrroleboronic acid is an organic synthesis intermediate used primarily in the synthesis of chiral pharmaceutical molecules and biologically active molecules. The boronic acid on the pyrrole ring can participate in Suzuki coupling reactions. The boronic acid can be oxidized to a hydroxyl group under the action of nitrogen oxides, and after tautomerization, it can be further transformed into 2-oxo-2,5-dihydro-1-pyrrolecarboxylic acid tert-butyl ester[1].

Product Specifications

CAS Number

[135884-31-0]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-boc-2-pyrroleboronic-acid.html

Purity

99.97

Solubility

DMSO : 175 mg/mL (ultrasonic)

Smiles

O=C(N1C(B(O)O)=CC=C1)OC(C)(C)C

Molecular Formula

C9H14BNO4

Molecular Weight

211.03

Precautions

H302, H315, H319, H335

References & Citations

[1]Tsutomu Fukuda, et al. synthesis and evaluation of topoisomerase I inhibitors possessing the 5,13-dihydro-6H-benzo[6,7]indolo[3,2-c]-quinolin-6-one scaffold. Heterocycles, 99 (2, Spec. Issue), 1032-1052; 2019.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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