T2AA hydrochloride
T2AA is a small molecule PCNA inhibitor that disrupts PCNA's interactions with partner proteins like p21, leading to replication inhibition, S-phase arrest, and sensitization to cisplatin-induced DNA damage. It is a valuable research tool for studying DNA replication, repair mechanisms, and combination therapies in cancer cell models like HeLa and U2OS.
Product Specifications
CAS Number
2138331-07-2
Field of Research
Cell Biology, Molecular Biology
Smiles
O (C1=C (I) C=C (C[C@@H] (CO) N) C=C1I) C2=CC=C (O) C=C2.Cl
Molecular Formula
C15H15I2NO3?HCl
Molecular Weight
547.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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