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T2AA hydrochloride

T2AA is a small molecule PCNA inhibitor that disrupts PCNA's interactions with partner proteins like p21, leading to replication inhibition, S-phase arrest, and sensitization to cisplatin-induced DNA damage. It is a valuable research tool for studying DNA replication, repair mechanisms, and combination therapies in cancer cell models like HeLa and U2OS.

Product Specifications

CAS Number

2138331-07-2

Field of Research

Cell Biology, Molecular Biology

Smiles

O (C1=C (I) C=C (C[C@@H] (CO) N) C=C1I) C2=CC=C (O) C=C2.Cl

Molecular Formula

C15H15I2NO3?HCl

Molecular Weight

547.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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