Daprodustat
Daprodustat (GSK1278863) is a small molecule inhibitor of HIF-prolyl hydroxylase (HIF-PH) . It stabilizes HIF-α, mimicking hypoxia to stimulate endogenous erythropoietin production, and is utilized in research on anemia, renal disease, and hypoxia-response pathways in both cellular and animal models.
Product Specifications
CAS Number
960539-70-2
Product Name Alternative
Daprodustat, inhibit, HIF, HIF ProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, Inhibitor, Hypoxia-inducible factors, HIFProlylHydroxylase, HIF-PH, HIFs, GSK 1278863, GSK1278863, GSK-1278863
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery
Purity
97.00% (May vary between batches)
Solubility
H2O:<1 mg/mL; DMSO:10 mg/mL (25.42 mM) ; Ethanol:<1 mg/mL
Smiles
OC (=O) CNC (=O) C1C (=O) N (C2CCCCC2) C (=O) N (C2CCCCC2) C1=O
Molecular Formula
C19H27N3O6
Molecular Weight
393.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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