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Vadadustat

Vadadustat is an orally active, titratable small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) . It is used in research to study anemia treatment mechanisms, demonstrating efficacy in both cellular assays and animal models of renal anemia.

Product Specifications

CAS Number

1000025-07-9

Product Name Alternative

Disease, chronic, anemia, AKB 6548, AKB6548, AKB-6548, inhibit, kidney, nondialysis-dependent, HIF/HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF, HIF-PH, HIF/HIFProlylHydroxylase, HIFs, HIFProlylHydroxylase, Inhibitor, Hypoxia-inducible factors, Erythropoiesis-stimulating, PG1016548, PG-1016548, PG 1016548, Vadadustat

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery

Purity

99.02% (May vary between batches)

Solubility

DMSO:100 mg/mL (326.05 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.04 mM)

Smiles

OC (=O) CNC (=O) c1ncc (cc1O) -c1cccc (Cl) c1

Molecular Formula

C14H11ClN2O4

Molecular Weight

306.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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