KW-2450 Formate
KW-2450 Formate is a dual IGF-1R/IR and Aurora kinase inhibitor. It exhibits antitumor activity by blocking Aurora A and B kinases, leading to tetraploidy and growth inhibition in triple-negative breast cancer (TNBC) xenograft models, supporting its use in oncology research.
Product Specifications
Product Name Alternative
Tyrosine kinase
Field of Research
Protein Biochemistry
Purity
99.28% (May vary between batches)
Smiles
O=C (C1=C (C) C=CS1) NC (C=C (C=C2) CN3CCN (CC3) C (CO) =O) =C2/C=C/C4=NNC5=CC=CC=C45.[H]C (O) =O
Molecular Formula
C29H31N5O5S
Molecular Weight
561.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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