AKE-72
AKE-72 is a small molecule pan-BCR-ABL inhibitor that suppresses the growth of Ba/F3 cells harboring native or T315I-mutant BCR-ABL. It is a research tool for studying kinase resistance mechanisms in chronic myeloid leukemia (CML) models, applicable in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
2566525-18-4
Product Name Alternative
BcrAbl, BCR-ABL, AKE72
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.30% (May vary between batches)
Smiles
O=C (NC1=CC=C (C (=C1) C (F) (F) F) CN2CCN (CC) CC2) C=3C=CC=C (C#CC4=CC=CC=5NN=C (N) C45) C3
Molecular Formula
C30H29F3N6O
Molecular Weight
546.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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